LUOYANG FUDAU BIOTECH CO.LTD.--Cell Culture Consumables

  Serum is a nutrient required for cell culture. There are many types of serum. In addition to the bovine serum we often say, horse serum is also commonly used. So which cells are this serum mainly used for, and what are the characteristics of the   PETG media bottle   as its container? Serum refers to the light yellow transparent liquid separated from the fibrin in the plasma after blood coagulation, or refers to the plasma from which the fibrin has been removed. The main function is to provide basic nutrients, hormones and various growth factors, binding proteins, contact-promoting and stretching factors to protect cells from mechanical damage and protect cells in culture. Horse serum is collected from healthy horse blood as raw material, aseptic blood collection in a closed system, and microporous filtration. It is a clear liquid, free of bacteriophage, ultra-low endotoxin, no hemolysis, no foreign matter, no bacteria, fungi, mycoplasma, mycoplasma, chlamydia, etc., pr...

May 19, 2023, the U.S. Food and Drug Administration approved Vyjuvek, a herpes-simplex virus type 1 (HSV-1) vector-based gene therapy, for the treatment of wounds in patients 6 months of age and older with dystrophic epidermolysis bullosa (DEB) with mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.  “Vyjuvek is the first FDA-approved gene therapy treatment for DEB, a rare and serious genetic skin disorder,” said Peter Marks, M.D., Ph.D., director of the FDA’s Center for Biologics Evaluation and Research. “Today’s action demonstrates the FDA’s ongoing commitment to supporting the development and evaluation of new treatments that address unmet needs for rare diseases or conditions.” PETG Media Bottles DEB is a genetic disorder that affects the connective tissue in the skin and nails and results from mutation(s) in the COL7A1 gene. This gene encodes type VII collagen (COL7), which is an essential protein that helps strengthen and stabilize the outer and middle layers o...

  Cell culture plates   are a kind of consumable with porous structure. The common ones are 4-well, 6-well, 24-well, 48-well, 96-well, etc. It is mainly used for exploring and optimizing the initial experimental conditions in cell and culture.  Cell culture experiment is a very rigorous work, which requires very high performance of consumables. For cell culture plates, it is mainly reflected in the following two aspects: 1. Adherence ability: This is a necessary condition for the growth of adherent cells. Different from the growth of suspension cells in the culture medium, the growth of adherent cells must have a support surface that can be attached. The cells rely on their own secretion or in the culture medium. The provided attachment factors can grow and reproduce on the surface. Cell culture plates generally use polystyrene raw materials, which are hydrophobic in nature. In order to adapt to the growth of adherent cells, they will undergo special surface modification....

  In suspension cell culture,   cell culture erlenmeyer flask   is commonly used as a cell culture consumable. The growth of suspension cells does not rely on the surface of the support and grows in a suspended state in the culture medium. In actual culture, how do we determine the amount of liquid to add? The common specifications of cell culture erlenmeyer flask include 125ml, 250ml, 500ml, and 1000ml, which meet the needs of different scales of cell culture. For example, 125ml and 250ml small-capacity bottles are mainly used for small-scale experiments, while 500ml and 1000ml specifications are used for medium-scale cell culture experiments. When this consumable is used, the vibration of the shaker is used to reduce the clumping rate of cells and maintain a good growth state of cells. Cell culture needs to be carried out in a sterile environment. Therefore, the triangular culture flask will undergo special sterilization treatment before it is put into use to achieve th...

May 10, 2023  the U.S. Food and Drug Administration (FDA) has approved Elfabrio (pegunigalsidase alfa-iwxj) in the United States for the treatment of adult patients with Fabry disease. "While much progress has been made in the treatment of Fabry disease, there is still a need for new treatment options," said Giacomo Chiesi, head of Chiesi Global Rare Diseases. "We established Chiesi Global Rare Diseases to deliver innovative therapies and solutions for people affected by rare diseases. With the FDA approval of Elfabrio, we can now offer people living with Fabry disease an alternative treatment option." Cell Factory "We are extremely pleased to receive FDA approval of Elfabrio for the treatment of adult patients with Fabry disease," said Dror Bashan, Protalix's President and Chief Executive Officer. "This approval is a testament to the dedication of the Protalix and Chiesi teams to deliver this much needed new therapeutic option to patients in need...

As a convenient cell culture container,   cell culture flasks   appear frequently in laboratories and are mainly used to cultivate adherent cells. When culturing cells, we need to observe the state of the cells and judge their growth. So, how should we observe? First of all, the state of the cells can be observed through eyes or a microscope. When we take out the cell culture flasks from the incubator, we can judge the growth of the cells by the color, concentration, and cell state of the medium. T25 Flask 1. Look at the color of the medium. There are acid-base indicators in most media, which are yellow when acidic and purple when alkaline. If the pH value of the medium changes greatly, consider whether the medium is contaminated, or the cells grow too densely, or the cells die too much, or there is a problem with the adjustment of the CO2 concentration in the incubator. 2. Look at the concentration of the medium. When the medium becomes turbid, the medium is contaminated or t...

  Fetal bovine serum is a commonly used supplementary medium in cell culture. It is rich in nutrients necessary for cell growth, and at the same time provides adhesion factors, detoxification, protease inhibitors, and protects cells from damage. There are many kinds of cells, which cells are the main uses of this serum, and how to choose the   media bottle   for storage? Although serum-free culture technology has been developed rapidly, many cell lines may not be applicable, cannot replicate all growth factors present in fetal bovine serum, and have disadvantages such as high development costs of serum-free medium. Fetal bovine serum can be used for research and production of almost all in vitro cultured mammalian cells, including drug discovery, diagnostics, toxicity testing, cell therapy, in vitro fertilization, human and animal vaccine production, etc. 60ml-Square-PETG-PET-Media-Bottles         We have already learned about the application of fetal ...