Sterilization methods and characteristics of media bottles

As a kind of cell culture consumables, media bottles have high requirements for their own sterility. Generally, they have been aseptically treated. The sterilization method used is electron beam sterilization. So what are the advantages of this sterilization method?

Electron beam irradiation is a technique commonly used for the sterilization of pharmaceutical packaging products and medical devices. It works by directing a continuous flow of electrons through the item being sterilized. It loses its activity and the irradiated article becomes sterile.

The e-beam sterilization method employed in media bottles has many advantages, being convenient, gentle, effective, and continuously performed on the final packaged product (such as those provided in nests used in flexible fillers). It operates at a much lower temperature than steam sterilization and is suitable for products with hard-to-reach areas (eg, cartridges with lids). Compared to gamma radiation, it has a much lower risk of degradation (due to shorter exposure times); compared to ethylene oxide exposure, it eliminates the risk of ethylene oxide absorption and subsequent penetration into the drug product.

Based on the above advantages, the birth of electron beam sterilization technology has made many products bid farewell to the use of high temperature and high pressure chemical sterilization. The use of this sterilization method for media bottles is not only convenient and fast, but also fundamentally ensures that the serum is in a good storage environment. Help the smooth progress of cell culture work.